Back كيناز الأسبارتات Arabic Aspartato cinasa Spanish Aspartate kinase French Aspartato chinasi Italian Aspartato quinase Portuguese Aspartat kinaza Serbo-Croatian Aspartat kinaza Serbian Аспартаткіназа Ukrainian
| Aspartate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Aspartate kinase homodimer, Arabidopsis thaliana | |||||||||
| Identifiers | |||||||||
| EC no. | 2.7.2.4 | ||||||||
| CAS no. | 9012-50-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Aspartate kinase or aspartokinase (AK) is an enzyme that catalyzes the phosphorylation of the amino acid aspartate. This reaction is the first step in the biosynthesis of three other amino acids: methionine, lysine, and threonine, known as the "aspartate family". Aspartokinases are present only in microorganisms and plants, but not in animals, which must obtain aspartate-family amino acids from their diet. Consequently, methionine, lysine and threonine are essential amino acids in animals.